Pedigree Analysis and Population Genetics 3 months ago
1. Setup and Data Preparation | 2. Pedigree Overview with pedstats() | 3. Pedigree Completeness with pedecg() | 4. Generation Intervals with pedgenint() | 5. Subpopulation Structure with pedsubpop() | 6. Diversity Indicators with pediv() | 6.1 fe, fa, and fg: what do they measure? | Effective number of founders (fe) | Effective number of ancestors (fa) | Founder genome equivalents (fg) | Retained genetic diversity (GeneDiv) | 6.2 Shannon-entropy effective numbers: feH and faH | Metric guide | Interpreting the ratio $f_e^{(H)} / f_e$ | Management implications | 7. Diversity Dynamics over Time with pedhalflife() | 7.1 Column guide for $timeseries | 7.2 Interpreting the $\lambda$ components | 7.3 Interpreting $T_{1/2}$ | 8. Effective Population Size with pedne() and pediv() | 8.1 Demographic Ne | 8.2 Inbreeding Ne | 8.3 Coancestry Ne | 9. Average Relationship Trends with pedrel() | 9.1 Mean additive relationship (scale = "relationship") | 9.2 Corrected mean coancestry (scale = "coancestry") | 10. Inbreeding Trends with inbreed() and pedfclass() | 11. Gene Flow and Partial Inbreeding | 11.1 pedancestry(): founder-line proportions | 11.2 pedpartial(): which ancestors explain inbreeding? | 12. Practical Interpretation | References
visPedigree 1.8.1Sheng Luan pedigree-analysis.Rmd